Regenerative Biologics

Globus Medical is focused on pioneering innovative regenerative solutions for patients with musculoskeletal disorders. Our comprehensive biologics portfolio includes cellular allografts, synthetic bone void fillers, demineralized bone products, amniotic barrier, graft delivery, and autologous biologic centrifuge technologies.

Cellular Allograft

Our cellular allografts contain viable cells including inherent stem cells and osteoprogenitor cells that are essential requirements for bone formation. Cellular products have many of the same characteristics as the gold standard of bone grafting, iliac crest bone graft, without the morbidity of autograft harvesting. The components of cellular allografts are intended to provide the three essential elements of bone formation: osteogenic cells, osteoconductive scaffold, and osteoinductive growth factors.

Osteocel Pro

Osteocel™ Pro

Osteocel™ Pro is a premier cellular allograft bone matrix designed to mimic the biological profile of autograft.

ViaCell

ViaCell™ Viable Cell Allograft

ViaCell™ is a cellular allograft comprised of partially demineralized cortical fibers and cancellous chips and includes inherent stem cells and osteoprogenitor cells.

Synthetic

Our synthetic biologics are optimized utilizing various technologies such as bovine collagen, bioglass, hydroxyapatite, and β-TCP to aid in bone formation while also delivering excellent handling properties.

Kinex

KINEX™ and KINEX™ PLUS Bioactive Bone Void Filler

The components of KINEX™ and KINEX™ PLUS Bioactive are designed to recruit and signal osteoblasts, help promote early vascular development, and bind proteins necessary for bone regeneration. KINEX™ uses The Power of Bioactive Glass™ to help promote bone formation and healing in the posterolateral spine*, pelvis, and extremities.

*KINEX™ Strip, KINEX™ Plus Strip, KINEX™ Putty and KINEX™ Gel are not indicated for use in the spine.

SIGNIFY

SIGNIFY™ Bioactive Bone Void Filler*

The components of SIGNIFY™ Bioactive are designed to recruit and signal osteoblasts that help promote bone formation. SIGNIFY™ provides an osteoconductive matrix to allow for new bone growth and contains activating chemistry designed to attract and stimulate bone cells.

*SIGNIFY™ Putty and Gel are not indicated for use in the spine.

Attrax™ Putty

Attrax™ Putty is a synthetic bone void filler designed to drive bone formation in the posterolateral spine, intervertebral disc space, and pelvis with a uniquely engineered bioactive and osteoconductive surface structure.

Attrax Scaffold

Attrax™ Scaffold

Attrax™ Scaffold is a synthetic, osteoconductive, resorbable bone void filler for the repair of bony defects in the posterolateral spine, intervertebral disc space, or pelvis, consisting of tricalcium phosphate/hydroxyapatite granules pre-mixed with type I bovine collagen.

Formagraft

Formagraft™ Collagen Bone
Graft Matrix

Formagraft™ Collagen Bone Graft Matrix is designed to provide a highly absorbent, compression-resistant matrix. Comprised of purified type 1 collagen and biphasic (β-TCP/HAp) granules, Formagraft™ delivers excellent handling properties and a controlled degradation rate.1

DBM/Allograft

Our DBM/allograft biomaterials provide a natural osteoconductive scaffold composed of 100% allograft bone without any added synthetic carrier. Use of cancellous bone or bone fibers helps provide a unique architecture with high surface area for osteoconductivity.

ViaSorb sponges

ViaSorb™ Demineralized Cancellous Sponges

ViaSorb™ Cubes and Strips are demineralized cancellous sponges that provide a natural osteoconductive scaffold with unique compressive capabilities that facilitate packing into bony voids and within allograft spacers.

Ossifuse

Ossifuse™ HSA Fiber Bone Graft

Ossifuse™ HSA Boats, Strips, and Putty are composed of 100% allograft bone without an added synthetic carrier. The demineralized cortical fibers in Ossifuse™ HSA have a unique architecture with a high surface area for cellular attachment and growth factor release.

Cancellous chips

Cancellous Chips

Available as cancellous chips, crushed cancellous chips, cortical cancellous chips, and demineralized cancellous chips, traditional bone allograft is derived from donated human cadaveric tissue and serves as a scaffold for new bone formation.

Amniotic Membrane

Our dual layer amnion patch is processed from human placental tissue. The protective properties of amnion make it an ideal barrier to protect soft tissue from the surrounding environment.

ViaShield

ViaShield™ Dual Layer Amnion Patch

ViaShield™ is a chorion-free, dual layer amnion patch processed from human placental tissue. The placental tissue is derived from live healthy donors at childbirth. The protective properties of amnion make it an ideal barrier to protect soft tissue from the surrounding environment.

Graft Delivery

Our graft delivery systems are designed for targeted delivery of graft materials in MIS applications. These systems allow for controlled delivery to streamline surgical workflow.

InstaFill

InstaFill™ Graft Delivery System

The InstaFill™ Graft Delivery System is designed to load and deliver synthetic bone graft, allograft, and autogenous bone graft quickly and efficiently.

Graft Delivery System

Graft Delivery System™

The Graft Delivery System™ is designed specifically for the delivery of Osteocel™ grafts into the disc space in minimally disruptive MAS™ PLIF/TLIF procedures.

ALLOCATE

ALLOCATE™ Cannula Kit

The ALLOCATE™ Cannula Kit provides instruments for consistent and controlled delivery of KINEX™ PLUS Bioactive Gel.

Autologous PRP/BMAC™/Adipose

The Harvest™ SmartPrep™ Centrifuge System is a FDA-cleared autologous biologic spin-down device capable of preparing bone marrow aspirate concentrate (BMAC™), platelet-rich plasma (PRP), and adipose-derived cellular biologics (AdiPrep™) in a seamless single-button operation. The flexibility in treatment options offers the ability to choose a biologic solution based on patient needs.

Harvest

Harvest™ SmartPrep™ 3 System

The Harvest™ SmartPrep™ 3 System is an autologous biologic centrifuge platform that generates highly concentrated platelet-rich plasma (PRP), bone marrow aspirate concentrate (BMAC™), and adipose-derived (AdiPrep™) cellular biologics.

  1. Walsh R, Vizesi F, Cornwall G, et al. Posterolateral spinal fusion in a rabbit model using a collagen-mineral composite bone graft substitute. Eur Spine J. 2009;18(11):1610–1620.