Cohere™ TLIF-A
Product Overview
Cohere™ TLIF-A is a porous PEEK posterior interbody designed for anterior column support and restoration of sagittal alignment.
Features and Benefits
Porous Surface
Porosity elicits a significantly stronger osteogenic response at the cellular level compared to roughened or nano-roughened surfaces on their own.1–4
Durable Structure
With a stiffness similar to bone, Cohere™ TLIF-A implants were shown to reduce stress shielding and risk of subsidence, compared with solid titanium implants in biomechanical testing.5
Created with Imaging in Mind
Leverages the radiolucent properties of PEEK to enable radiographic visualization on a variety of imaging modalities.
1. Cheng A, Humayun A, Cohen DJ, et al. Additively manufactured 3d porous TI-6AL-4V constructs mimic trabecular bone structure and regulate osteoblast proliferation, differentiation and local factor production in a porosity and surface roughness dependent manner. Biofabrication. 2014;6:045007.
2. Cheng A, Humayun A, Boyan BD, et al. Enhanced osteoblast response to porosity and resolution of additively manufactured TI-6AL-4V constructs with trabeculae-inspired porosity. 3D Print Addit Manuf. 2016;3:10-21.
3. Cheng A, Cohen DJ, Kahn A, et al. Laser sintered porous TI-6AL-4V implants stimulate vertical bone growth. Ann Biomed Eng. 2017;45:2025-35.
4. Cheng A, Cohen DJ, Boyan BD, et al. Laser-sintered constructs with bio-inspired porosity and surface micro/nano-roughness enhance mesenchymal stem cell differentiation and matrix mineralization in vitro. Calcif Tissue Int. 2016;99:625-37.
5. Carpenter RD, Klosterhoff BS, Torstrick FB, et al. Effect of porous orthopaedic implant material and structure on load sharing with simulated bone ingrowth: A finite element analysis comparing titanium and PEEK. J Mech Behav Biomed Mater. 2018;80:68-76.
