Product Overview

Cohere™ ALIF is a porous PEEK integrated anterior lumbar interbody fusion (ALIF) spacer intelligently designed to promote bone ingrowth while maintaining the inherent biomechanical and imaging properties of PEEK.1,2

Features and Benefits


Porous Surface

As demonstrated in animal testing, porous endplates are designed to promote new bone ongrowth and ingrowth,3 leading to greater integration strength than smooth PEEK.4,5

Durable Structure

Cohere™ ALIF is designed to mimic the architecture and stiffness of bone, maintain high porosity under conditions that replicate anatomic loading, and resist abrasion damage and delamination under impacted insertion.6,7

Created with Imaging in Mind

Cohere™ ALIF leverages the radiolucent properties of PEEK to enable radiographic visualization on a variety of imaging modalities.

 

 

1. Preclinical data on file; data may not be representative of clinical results.
2. Cheng A, Humayun A, Boyan BD, et al. Enhanced osteoblast response to porosity and resolution of additively manufactured ti-6al-4v constructs with trabeculae-inspired porosity. 3D Print Addit Manuf. 2016;3(1):10–21.
3. Torstrick FB, Safranski DL, Burkus JK, et al. Getting PEEK to stick to bone: the development of porous PEEK for interbody fusion devices. Tech Orthop. 2017;32:158-166.
4. Torstrick FB, Lin ASP, Gall K, et al. Porous PEEK improves the bone-implant interface compared to plasma-sprayed titanium coating in PEEK: in vitro and in vivo analysis. Transactions of the 2017 Annual Meeting of the ORS, San Diego, CA; Poster 0835.
5. Torstrick FB, Evans NT, Stevens HY, et al. Do surface porosity and pore size influence mechanical properties and cellular response to PEEK? Clin Orthop Relat Res. 2016;474(11):2373-2383.
6. Evans NT, Torstrick FB, Safranski DL, et al. Local deformation behavior of surface porous polyether-ether-ketone. J Mech Behav Biomed Mater. 2017;65:522-532.
7. Torstrick FB, Klosterhoff BS, Westerlund LE, et al. Impaction durability of porous poly-ether-ketone (PEEK) and titanium-coated PEEK interbody fusion devices. Spine J. 2018;18(5):857-865.

Visit nuvasive.com/eifu for important product safety information.