ACDF | ALIF | LLIF | PLIF | TLIF
HEDRON™ 3D printed titanium interbody spacers feature a biomimetic porous scaffold designed to promote bone formation onto and through the implant.



TRABECULAR BONE
INSPIRED DESIGN
Osseointegration between an implant and surrounding bone may help achieve stability. HEDRON™ integrates biomimetic architecture with characteristics of established interbody fusion devices.
Strength and Porosity
Unlike first generation 3D printed implants (grid and open architecture), HEDRON™ strikes the ideal balance of strength and porosity through a sturdy frame and pore size distribution similar to trabecular bone.
2. Torres-Sanchez et al. Material Science and Engineering. 2017 Mar; 219–228.
3. KKarageorgiou V, Kaplan D. Biomaterials. 2005;26(27):5474-91.
ENCOURAGES CELLULAR
RESPONSE
In Vitro testing demonstrated that HEDRON™ generated a greater expression of Vascular Endothelial Growth Factor (VEGF) and Osteocalcin, two biological indicators of bone formation when seeded with osteoblasts.4
SEM images of cell proliferation at 21 days (500x magnification)
4. Cell study data on file.
PROMOTES BONE
FORMATION
Unlike PEEK and TAV, the porous architecture of HEDRON™ allows for bone to grow through the spacer walls and incorporate into the fusion mass. In a pre-clinical ovine study, HEDRON™ implants showed significantly more bone growth compared to PEEK and titanium implants at 6-weeks post-op.5
A pre-clinical sheep interbody study using HEDRON™, Titanium (Ti), and PEEK implants was performed to compare bone ingrowth and ongrowth.


5. Animal study data on file.
*p<0.05 vs PEEK.
†p<0.05 vs TAV