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THE FACE OF FUSION

ACDF | ALIF | LLIF | PLIF | TLIF

HEDRON™ 3D printed titanium interbody spacers feature a biomimetic porous scaffold designed to promote bone formation onto and through the implant.

TRABECULAR BONE
INSPIRED DESIGN

Osseointegration between an implant and surrounding bone may help achieve stability. HEDRON™ integrates biomimetic architecture with characteristics of established interbody fusion devices.

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MicroCT of trabecular bone
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SEM image of HEDRON™
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Clear visualization

Supplemental fixation required.

FEATURES

Lattice stiffness comparable to trabecular bone1

70% porosity

Expansive pore size distribution

Roughened surface texture

1. Mechanical study data on file.

Strength and Porosity

Unlike first generation 3D printed implants (grid and open architecture), HEDRON™ strikes the ideal balance of strength and porosity through a sturdy frame and pore size distribution similar to trabecular bone.

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Grid

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Open architecture

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HEDRON™

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ONGROWTH

<300μm

Small pores (<300μm) are recommended to support initial surface adhesion2

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BONE FORMATION

>300μm

Large pores (>300μm) have been shown to lead to direct osteogenesis3

2. Torres-Sanchez et al. Material Science and Engineering. 2017 Mar; 219–228.
3. KKarageorgiou V, Kaplan D. Biomaterials. 2005;26(27):5474-91.

ENCOURAGES CELLULAR
RESPONSE

In Vitro testing demonstrated that HEDRON™ generated a greater expression of Vascular Endothelial Growth Factor (VEGF) and Osteocalcin, two biological indicators of bone formation when seeded with osteoblasts.4

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SEM images of cell proliferation at 21 days (500x magnification)

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PEEK

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TAV

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HEDRON™

4. Cell study data on file.

PROMOTES BONE
FORMATION

Unlike PEEK and TAV, the porous architecture of HEDRON™ allows for bone to grow through the spacer walls and incorporate into the fusion mass. In a pre-clinical ovine study, HEDRON™ implants showed significantly more bone growth compared to PEEK and titanium implants at 6-weeks post-op.5

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A pre-clinical sheep interbody study using HEDRON™, Titanium (Ti), and PEEK implants was performed to compare bone ingrowth and ongrowth.

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5. Animal study data on file.

*p<0.05 vs PEEK.

†p<0.05 vs TAV

Accommodates Multiple Approaches and Techniques

Procedure HEDRON™ Spacer Footprint Heights Lordosis
ACDF HEDRON C 12x14, 14x16, 15x18mm 5, 6, 7, 8, 9, 10, 11, 12mm 0°, 7°, 12°, 15°, 20°
HEDRON IC 12x14, 14x16, 15x18mm 5, 6, 7, 8, 9, 10, 11, 12mm 0°, 7°, 12°
ALIF HEDRON A 22x29, 24x35, 28x39mm 9, 11, 13, 15, 17, 19, 21mm 8°, 15° and 20°
HEDRON IA 24x30, 26x34, 29x39mm 11, 13, 15, 17, 19, 21mm 8°, 15°, 20°, 25°, and 30°
LLIF HEDRON L 18, 22mm widths 40–60mm heights 7, 9, 11, 13, 15mm 10°, 15°
PLIF HEDRON P 8x22, 10x22, 10x26, 10x30, 12x26, 12x30mm 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17mm 8°, 15°
TLIF HEDRON T 10x28, 11x33mm 7, 8, 9, 10, 11, 12, 13, 15, 17mm 8°, 15°