{"id":1102,"date":"2019-02-01T19:15:31","date_gmt":"2019-02-01T19:15:31","guid":{"rendered":"https:\/\/www.globusmedical.com\/expandabletechnology\/?page_id=1102"},"modified":"2020-07-16T17:25:15","modified_gmt":"2020-07-16T17:25:15","slug":"altera-massie","status":"publish","type":"page","link":"https:\/\/www.globusmedical.com\/expandabletechnology\/altera-massie\/","title":{"rendered":"Clinical: ALTERA Massie et al. 2018"},"content":{"rendered":"\r\n<section class=\"sh-section sh-section-a1915be58170e622aa1acbdb322a9f19 fw-main-row sh-section-visibility-everywhere\">\r\n\t\r\n\t\r\n\t<div class=\"sh-section-container container\">\r\n\t\t<div class=\"fw-row\">\n\t\r\n<div class=\"sh-column sh-column-1b4e4ad48d134e09cc07a3333f656f71 fw-col-xs-12\" >\r\n\r\n\t\r\n\t<div class=\"sh-column-wrapper\">\r\n\t\t\r\n<div id=\"text-block-129ccc7d1a879e4cf3e81091d2a5bd41\" class=\"sh-text-block\">\r\n\t<p style=\"text-align: center;\">Neurosurg Focus. 2018 Jan;44(1):E8. doi: 10.3171\/2017.10.FOCUS17562.<\/p><\/div>\r\n\r\n<div id=\"text-block-c00e45dd9153b25006bc7c545ecdf690\" class=\"sh-text-block\">\r\n\t<h2 style=\"text-align: center;\">Assessment of radiographic and clinical outcomes of an articulating expandable interbody cage in minimally invasive transforaminal lumbar interbody fusion for spondylolisthesis.<\/h2><\/div>\r\n\r\n<div id=\"text-block-1d8d1d2f43696990e91b3d218127f8d2\" class=\"sh-text-block\">\r\n\t<p style=\"text-align: center;\">Massie LW(1), Zakaria HM(1), Schultz LR(2), Basheer A(1), Buraimoh MA(3), Chang V(1).<\/p><\/div>\r\n\r\n<div id=\"divider-e2c0a14c10a1e69c6f21a41cd504d48b\" class=\"sh-divider sh-divider-center sh-divider-content-none\">\r\n\t\t\t<div class=\"sh-divider-line\"><\/div>\r\n\t<\/div>\r\n\r\n<div id=\"text-block-84ba8cb18a9e19358dd774232c529cea\" class=\"sh-text-block\">\r\n\t<p>Author information:<br \/><sup>1<\/sup>Departments of Neurosurgery and.<br \/><sup>2<\/sup>Public Health Sciences, Henry Ford Health System, Detroit, Michigan; and.<br \/><sup>3<\/sup>Department of Orthopedics, University of Maryland, Baltimore, Maryland.<\/p><p><strong>OBJECTIVE<\/strong><\/p><p>The inability to significantly improve sagittal parameters has been a limitation of minimally invasive surgery for transforaminal lumbar interbody fusion (MIS TLIF). Traditional cages have a limited capacity to restore lordosis. This study evaluates the use of a crescent-shaped articulating expandable cage (Altera) for MIS TLIF.<\/p><p><strong>METHODS<\/strong><\/p><p>This is a retrospective review of 1- and 2-level MIS TLIF. Radiographic outcomes included differences in segmental and lumbar lordosis, disc height, evidence of fusion, and any endplate violations. Clinical outcomes included the numeric rating scale for leg and back pain and the Oswestry Disability Index (ODI) for low-back pain.<\/p><p><strong>RESULTS<\/strong><\/p><p>Thirty-nine patients underwent single-level MIS TLIF, and 5 underwent 2-level MIS TLIF. The mean age was 63.1 years, with 64% women. On average, spondylolisthesis was corrected by 4.3 mm (preoperative = 6.69 mm, postoperative = 2.39 mm, p &lt; 0.001), the segmental angle was improved by 4.94\u00b0 (preoperative = 5.63\u00b0, postoperative = 10.58\u00b0, p &lt; 0.001), and segmental height increased by 3.1 mm (preoperative = 5.09 mm, postoperative = 8.19 mm, p &lt; 0.001). At 90 days after surgery the authors observed the following: a smaller postoperative sagittal vertical axis was associated with larger changes in back pain at 90 days (r = -0.558, p = 0.013); a larger decrease in spondylolisthesis was associated with greater improvements in ODI and back pain scores (r = -0.425, p = 0.043, and r = -0.43, p = 0.031, respectively); and a larger decrease in pelvic tilt (PT) was associated with greater improvements in back pain (r = -0.548, p = 0.043). For the 1-year PROs, the relationship between the change in PT and changes in ODI and numeric rating scale back pain were significant (r = 0.612, p = 0.009, and r = -0.803, p = 0.001, respectively) with larger decreases in PT associated with larger improvements in ODI and back pain. Overall for this study there was a 96% fusion rate. Fourteen patients were noted to have endplate violation on intraoperative fluoroscopy during placement of the cage. Only 3 of these had progression of their subsidence, with an overall subsidence rate of 6% (3 of 49) visible on postoperative CT.<\/p><p><strong>CONCLUSIONS<\/strong><\/p><p>The use of this expandable, articulating, lordotic, or hyperlordotic interbody cage for MIS TLIF provides a significant restoration of segmental height and segmental lordosis, with associated improvements in sagittal balance parameters. Patients treated with this technique had acceptable levels of fusion and significant reductions in pain and disability.<\/p><p>DOI: 10.3171\/2017.10.FOCUS17562<br \/>PMID: 29290133<\/p><\/div>\r\n\t<\/div>\r\n\r\n\r\n\t\t\r\n\r\n<\/div>\r\n<\/div>\n\n\t<\/div>\r\n<\/section>\r\n\n","protected":false},"excerpt":{"rendered":"<p>Neurosurg Focus. 2018 Jan;44(1):E8. doi: 10.3171\/2017.10.FOCUS17562. Assessment of radiographic and clinical outcomes of an articulating expandable interbody cage in minimally invasive transforaminal lumbar interbody fusion for spondylolisthesis. Massie LW(1), Zakaria HM(1), Schultz LR(2), Basheer A(1), Buraimoh MA(3), Chang V(1). Author information:1Departments of Neurosurgery and.2Public Health&#8230;<\/p>\n","protected":false},"author":2243,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-1102","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Clinical: ALTERA Massie et al. 2018 - Expandable Technology<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.globusmedical.com\/expandabletechnology\/altera-massie\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Clinical: ALTERA Massie et al. 2018 - Expandable Technology\" \/>\n<meta property=\"og:description\" content=\"Neurosurg Focus. 2018 Jan;44(1):E8. doi: 10.3171\/2017.10.FOCUS17562. Assessment of radiographic and clinical outcomes of an articulating expandable interbody cage in minimally invasive transforaminal lumbar interbody fusion for spondylolisthesis. Massie LW(1), Zakaria HM(1), Schultz LR(2), Basheer A(1), Buraimoh MA(3), Chang V(1). 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Assessment of radiographic and clinical outcomes of an articulating expandable interbody cage in minimally invasive transforaminal lumbar interbody fusion for spondylolisthesis. Massie LW(1), Zakaria HM(1), Schultz LR(2), Basheer A(1), Buraimoh MA(3), Chang V(1). 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